Director, Software and Data Engineering

We’re looking for a Director of Software and Data Engineering to lead Profluent’s software engineering function and build the platform connecting AI-driven protein design, high-throughput experimental screening, and quantitative data analysis.

You’ll own the software and data architecture connecting computational designs to the constructs, samples, assays, and measurements generated through automated laboratory workflows. Your team will build the scientist-facing tools, integrations, and data systems needed to manage experimental data at scale, preserve lineage and context, and turn results into reliable inputs for analysis, machine learning, and the next round of design.

The ideal candidate is an experienced engineering leader with a strong technical foundation, sound judgment, and a track record of building scalable data platforms. You’ll manage and mentor a small team while remaining close to architecture, data modeling, and technical decision-making, partnering across science, automation, data, and ML to advance Profluent’s lab-in-the-loop platform.

• High-growth opportunity with meaningful impact on the future of protein design

• Competitive compensation package with equity participation

• 401(k) with a strong employer match

• Comprehensive benefits including health/dental/vision insurance

• Generous PTO policy and commitment to work-life balance

• Professional development opportunities in a cutting-edge field at the intersection of AI and biology

Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.

Work Authorization Requirement

Applicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position.

Employment Eligibility Verification

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.

Hiring Salary Range

$268,000—$355,000 USD

NOTICE TO STAFFING AND SEARCH FIRMS: Profluent does not accept unsolicited candidate submissions. We ask that agencies refrain from sending resumes to our careers inbox, hiring managers, or any Profluent employee. Any resume submitted without a signed agreement and an active search request from our Talent team will be treated as the property of Profluent, and no placement fee will be owed.