Engineer II, Conjugation Development and Manufacturing

JOIN OUR MISSION TO PROTECT HUMANKIND!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHAT we do is every bit as important as HOW we do it! Our work together is

guided by four enduring core values

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet

of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the

most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive

approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE:  The magnitude of our challenge requires our shared

commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

SUMMARY

Vaxcyte is seeking a highly motivated and technically proficient Engineer II to join the Conjugation Process Development and Manufacturing group within the CMC organization. This individual will contribute to the development, scale up, and manufacturing of Vaxcyte’s multi valent polysaccharide based conjugate vaccines, which leverage a novel carrier protein produced through cell free synthesis. Conjugation—the covalent linkage of polysaccharide antigens to carrier proteins—is a critical component of Vaxcyte’s vaccine platform, and this role will support both laboratory development and cGMP manufacturing activities.

The successful candidate will bring hands on laboratory experience, a solid understanding of bioprocess operations, and practical exposure to cGMP environments, ideally within late-stage development. This position requires close collaboration with cross functional CMC teams, active participation in production campaigns, and the ability to independently execute development experiments and document technical findings. The role offers a unique opportunity to contribute directly to the advancement of Vaxcyte’s vaccine programs while developing deep expertise in conjugation process development and manufacturing.

ESSENTIAL FUNCTIONS

Reports to: Staff Engineer, Conjugation Development and Manufacturing

Location: San Carlos, CA

Work Arrangement: Onsite 5 days per week

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $146,000 – $171,000 (SF Bay Area). Salary ranges for

non-California locations may vary.

Equal Opportunity

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

Recruitment Fraud Notice

Please be aware of fraud or scams from individuals, organizations and/or internet sites claiming to represent Vaxcyte in recruitment activities. Vaxcyte has an established recruitment process for all positions prior to issuing an offer for employment and we will never extend unsolicited employment offers or ask candidates to provide financial or sensitive personal information as part of the application process. All legitimate communication from Vaxcyte will come from an official @vaxcyte.com email address. Qualified and interested candidates should apply to current openings at vaxcyte.com/careers vaxcyte.com/careers/.